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1.
Article | IMSEAR | ID: sea-221143

ABSTRACT

The street garments vendors are one of the constituent pillars of the giant unorganised workforce. They are the selfemployed category contributing a significant share to the economy of each country. The street garments vendors face many problems in the daily chores of their vending activities. The present study is conducted to examine the problems of street garments vendors in Chittoor District of Andhra Pradesh. Four hundred and fifty samples were drawn from the universe under simple random sampling method. The results show that women are dominating the street vending trades. The major problems include sexual harassment, physical evictions by the enforcement authorities. There is a significant relationship between the problems faced by the respondents and their overall perception about the street garments vendors. The study concludes that the Government of Andhra Pradesh has implemented more than 75 per cent of the provisions of the street garments vendors Act. The study ends with the concluding note that the Street garments vendors Act is to be implemented in letter and spirit to minimise the problems and issues against the street garments vendors in Chittoor District

2.
Article | IMSEAR | ID: sea-199813

ABSTRACT

A subset of HIV-1 infected patients undergoing Highly Active Antiretroviral Therapy (HAART) develops a lipodystrophy syndrome. It is characterised by loss of subcutaneous adipose tissue (face, limbs and buttocks) visceral fat accumulation and lipomatosis especially in dorsocervical area. In addition these patients show metabolic alteration implicative of metabolic syndrome particularly dyslipidaemia and insulin resistance. These alterations lead to enhanced cardiovascular risk and favour the development of diabetes in such patients. A complex combination of HIV infection, drug treatment related events and lipotoxicity appears to contribute to the development of lipodystrophy syndrome. Active lipolysis in subcutaneous fat combined with impaired storage capacity in subcutaneous depot leads to ectopic deposition of lipids either in visceral or in non-adipose sites. Lipotoxicity, a pathogenic factor in the lipodystrophy syndrome should be considered in the strategies for treating and /or preventing the morphological alterations and systemic metabolic disturbances associated with lipodystrophy.

3.
Article | IMSEAR | ID: sea-199809

ABSTRACT

Drug induced adverse reactions are a major health problem. Drug hyper sensitivity reactions manifest themselves in many diseases, of which some are very severe. The most common allergic reactions occur in the skin. Stevens-Johnson syndrome is mainly caused by drugs (antimicrobials e.g.: penicillin抯, sulphonamides and cephalosporin抯 e.g.: cefixime, antiepileptic抯, NSAIDS), infections and also by other risk factors not yet identified. The most common allergic reactions occur in the skin. These reactions ranging from simple pruritic eruptions to potentially life threatening events are a significant cause of iatrogenic morbidity and mortality. Identification of the cause, withdrawal of the trigger and supportive management is crucial to improve the patient state. Despite of all therapeutic efforts, mortality is high and increases with disease severity, patient抯 age and underlying medical conditions. Survivors may suffer from long-term squeal such as strictures of mucous membranes including severe eye problems.

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